SOX9 AS A TARGET FOR FIBROSIS THERAPY

摘要

Inappropriate expression of the transcription factor SOX9 has been linked to liver fibrosis providing an attractive new target for halting progress of liver fibrosis to cirrhosis. It is extrapolated that abrogation of SOX9 expression may also be used to treat other fibrotic conditions, notably, for example, skin keloid and other skin disorders associated with scarring.