BACTERIAL PRODUCTION OF HYDROPHOBIC POLYPEPTIDE

摘要

PROBLEM TO BE SOLVED: To provide a production method of interferon-β polypeptide by bacterial cells.

SOLUTION: A production method of interferon-β polypeptide by bacterial cells, by culturing cells producing IFN-β polypeptide under conditions that induce increased production of IFN-β polypeptide, is provided. Such conditions include, for example, low potassium cation concentration and/or very low sodium cation concentration and/or specific pH ranges.

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