METHOD FOR PRODUCING PHARMACEUTICAL TABLET

摘要

Disclosed is a method for producing a tablet which is improved in dissolvability, while having excellent productivity and stability to change over time. Specifically disclosed is a method for producing a tablet in which a morphinan compound represented by the general formula (I) below or a pharmacologically acceptable acid addition salt thereof and an acidic substance such as fumaric acid, maleic acid or adipic acid are blended. This method for producing a tablet is characterized in that the morphinan compound or a pharmacologically acceptable acid addition salt thereof is granulated together with an excipient before being blended with theacidic substance.