| 发明名称 |
QUINOLINE DERIVATIVES AS PI3 KINASE INHIBITORS |
| 摘要 |
<p>Invented is a method of inhibiting the activity/function of PB kinases using quinoline derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative discase, allergy, asthma, pancreatitis, multiorgan failure , kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by th e administration of quinoline derivatives.</p> |
| 申请公布号 |
CA2686016(A1) |
申请公布日期 |
2008.11.27 |
| 申请号 |
CA20082686016 |
申请日期 |
2008.05.16 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
ADAMS, NICHOLAS D.;SCHMIDT, STANLEY J.;KNIGHT, STEVEN DAVID;DONATELLI, CARLA A.;NEWLANDER, KENNETH ALLEN;RIDGERS, LANCE;SARPONG, MARTHA;BURGESS, JOELLE LORRAINE;DARCY, MICHAEL GERARD |
| 分类号 |
C07D401/14;A61K31/4709;A61K31/495;A61K31/5377;A61P35/00;C07D401/10;C07D405/14;C07D413/14;C07D471/04;C07D493/04;C07D498/04 |
主分类号 |
C07D401/14 |
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