发明名称 NOVEL COMPOSITIONS COMPRISING A PHOSPHODIESTERASE-5 INHIBITOR AND THEIR USE IN METHODS OF TREATMENT
摘要 The invention relates generally to novel pharmaceutical methods for the t reatment of various conditions. Compositions comprising: at least one phosph odiesterase-5-inhibitor in combination with one or more of the following med ications: a selective serotonin reuptake inhibitor; a serotonin-norepinephri ne reuptake inhibitor; a cholinesterase inhibitor; a dopamine agonist; or a medication suitable to increase the chemical concentrations of the neurotran smitters, selected from amino acids, monoamines, neuropeptides and other age nts capable of primary neurotransmission in the synaptic clefts, and their u se for treating a neurodegenerative disease in a subject. The invention also relates to: Compositions comprising: at least one phosphodiestersa-5-inhibi tor in combination with one or more of the following medications: a selectiv e serotonin reuptake inhibitor; or a cholinesterase inhibitor, and their use for treating damaged skin in a subject.
申请公布号 CA2687679(A1) 申请公布日期 2008.11.27
申请号 CA20082687679 申请日期 2008.05.19
申请人 VIVUS, INC. 发明人 HELD, JERRY M.
分类号 A61K31/15;A61K31/473;A61K31/4985;A61K45/06;A61P25/00;A61P25/16;A61P25/28 主分类号 A61K31/15
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