发明名称 Nanoscale Neuromodulating Platform For Retina Neuron Activation Apparatus and Method
摘要 Postsynaptic membrance receptor proteins of retinal neurons proximal to the rods and cones mediate the transmission of visual signals at multiple types of chemical synapses in the normally functioning retina, and there is reason to believe that these proximal retinal neurons in certain cases remain functional despite the disease-induced loss of rod and cone visual signaling. The invention is a nanoscale molecular structure that can selectively attach to the extracellular face of specific membrane receptors of post-photoreceptor retinal neurons and, by modulating the postsynaptic receptor's activity in response to light, restore visual signaling in retina damaged by photoreceptor degenerative disease.
申请公布号 US2008293915(A1) 申请公布日期 2008.11.27
申请号 US20060912754 申请日期 2006.04.28
申请人 THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 发明人 PEPPERBERG DAVID R.
分类号 C07K2/00;C07C245/06;C07D261/12 主分类号 C07K2/00
代理机构 代理人
主权项
地址