| 发明名称 |
Chemical Synthesis of a Highly Potent Epothilone |
| 摘要 |
A highly active synthetic epothilone compound whose activity exceeds that of either epothilone EpoA or EpoB when assayed as a cytotoxic agent against a cancer cell line is disclosed as is a pharmaceutical composition containing the synthetic epothilone.
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| 申请公布号 |
US2008293747(A1) |
申请公布日期 |
2008.11.27 |
| 申请号 |
US20060092038 |
申请日期 |
2006.11.09 |
| 申请人 |
NICOLAOU KYRIACOS C;PRATT BENJAMIN;ARSENIYADIS STELLIOS |
发明人 |
NICOLAOU KYRIACOS C.;PRATT BENJAMIN;ARSENIYADIS STELLIOS |
| 分类号 |
A61K31/52;A61K31/41;A61K31/415;A61K31/4164;A61K31/4196;A61K31/426;C07D257/04;C07D277/02;C07D405/02;C07D417/02;C07D473/00 |
主分类号 |
A61K31/52 |
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