The present invention relates to compounds and methods for inducing neuronal differentiation in normal neural stem cells and brain cancer stem cells. The methods may take place in vitro, such as in isolates from the adult mammalian brain, or in vivo. Compounds and methods described herein may find use in the treatment of neurodegenerative and psychiatric diseases, the repair and regeneration of the nervous system, and in treatment of neurologic malignancy.
申请公布号
WO2008046072(A3)
申请公布日期
2008.11.27
申请号
WO2007US81304
申请日期
2007.10.12
申请人
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM;SCHNEIDER, JAY;HSIEH, JENNY;FRANTZ, DOUGLAS;MCKNIGHT, STEVEN, L.;READY, JOSEPH, M.
发明人
SCHNEIDER, JAY;HSIEH, JENNY;FRANTZ, DOUGLAS;MCKNIGHT, STEVEN, L.;READY, JOSEPH, M.