| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method useful for controlling the gene expression of hepatitis C virus (HCV) in the use for various uses such as therapeutic treatment, diagnosis, target evaluation and genome discovery, and to provide a reagent for the method. <P>SOLUTION: There provided are small nucleic acid molecules mediating RNA interference (RNAi) against gene expression and/or activity of hepatitis C virus (HCV), such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules. The small nucleic acid molecule is useful for the treatment of HCV infection, hepatic insufficiency, hepatocyte carcinoma, hepatocirrhosis and arbitrary other diseases dealing with the control of the expression or activity of HCV. <P>COPYRIGHT: (C)2009,JPO&INPIT |
