In certain embodiments, the present invention relates to a process for preparing skin removed from a human donor and removing cellular components and forming a decellular matrix having as major components collagens and elastins while disinfecting the tissue. In a particular embodiment, the process comprises the following: (1) removing hair from the skin; (2) decellularizing the skin including inspection for visual defects; (3) soaking the tissue in a detergent and rinsing same with sterile water; (4) disinfecting the skin in a disinfection solution containing about 0.5% to about 0.7% peracetic acid; and (5) processing the tissue by cutting the tissue to size.
申请公布号
WO2008097885(A3)
申请公布日期
2008.11.27
申请号
WO2008US52885
申请日期
2008.02.04
申请人
NGO, MANH-DAN;GERTZMAN, ARTHUR;KAWAS, MICHAEL;TRUNCALE, KATHERINE, G.;SUNWOO, MOON, HAE
发明人
NGO, MANH-DAN;GERTZMAN, ARTHUR;KAWAS, MICHAEL;TRUNCALE, KATHERINE, G.;SUNWOO, MOON, HAE