| 摘要 |
Compounds of formula: (I) wherein A, B and D are respectively selected from the group consisting of: (i) CH, NH, C; (ii) CH, N, N; and (iii) CH, O, C; the dotted lines represent two double bonds in the appropriate locations; and where Z is selected from S, O, C(=O), CH; and NH are disclosed for use in inhibiting DNA-PK., (I) |
| 申请人 |
KUDOS PHARMACEUTICALS LIMITED;CANCER RESEARCH TECHNOLOGY LIMITED |
发明人 |
SMITH, GRAEME CAMERON MURRAY;MARTIN NIALL MORRISON BARR;HUMMERSONE, MARC GEOFFREY;MENEAR, KEITH ALLAN;COCKCROFT, XIAO-LING FAN;FRIGERIO, MARK;GRIFFIN, ROGER JOHN;GOLDING, BERNARD THOMAS;HARDCASTLE, IAN ROBERT;NEWELL, DAVID RICHARD;CALVERT, HILARY ALAN;CURTIN, NICOLA JANE;SARAVANAN, KAPPUSAMY;DESAGE-EL MURR, MARINE |
