发明名称 CHELATING CONJUGATES HAVING A SUBSTITUTED AROMATIC MOIETY AND DERIVATIVES THEREOF
摘要 A conjugate comprising a bio-directing carrier, a metal coordinating moiety, and a linker chemically linking the metal coordinating moiety to the carrier, the metal coordinating moiety comprising at least one optionally substituted 4,6-dihydroxypyrimidyl, 4,6-dithiolpyrimidyl, 4-thiol-6-hydroxypyrimidyl, 4-hydroxy-6-thiolpyrimidyl, 3,5-dihyroxypyridyl, 2,4-dihydroxypyridyl, 3,5-dithiolpyridyl, 2,4-dithiolpyridyl, 3-hydroxy-5-thiolpyridyl, 2-hydroxy-4-thiolpyridyl, 3-thiol-5-hydroxypyridyl, 2-thiol-4-hydroxypyridyl, 1,3-dithiolphenyl, 1-hydroxy-3-thiolphenyl or 1-thiol-3-hydroxyphenyl moiety, or a combination thereof.
申请公布号 EP1993613(A2) 申请公布日期 2008.11.26
申请号 EP20070753161 申请日期 2007.03.14
申请人 MALLINCKRODT, INC. 发明人 MOORE, DENNIS, A.
分类号 A61K49/00;A61K47/48;A61K51/04;A61K51/08 主分类号 A61K49/00
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