发明名称 |
Composizioni farmaceutiche di anticorpi anti-cd40 antagonisti |
摘要 |
<p>Stable liquid pharmaceutical compositions comprising an antagonist anti-CD40 antibody as a therapeutically or prophylactically active component and methods useful in their preparation are provided. These compositions comprise the antagonist anti-CD40 antibody, a buffering agent to maintain the pH of the composition between about pH 5.0 and about pH 7.0, and an amount of arginine-HCl sufficient to render the liquid composition near isotonic. The stable liquid antagonist anti-CD40 antibody-containing pharmaceutical compositions of the invention find use in methods for treating proliferative diseases and diseases having an autoimmune and/or inflammatory component.</p> |
申请公布号 |
SMAP200800064(A) |
申请公布日期 |
2008.11.26 |
申请号 |
SM20080000064T |
申请日期 |
2007.04.17 |
申请人 |
NOVARTIS AG;XOMA TECHNOLOGY LTD |
发明人 |
LU XIAOFENG;CHEN BAO-LU;ARAYA KIDISTI;OKHAMAFE AUGUSTUS |
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