发明名称 |
ASYMMETRIC CATALYTIC HYDROGENATION OF PROCHIRAL KETONES AND ALDEHYDES |
摘要 |
<p>Process for stereoselective hydrogenation by reacting racemic aldehydes or ketones having a stereogenic carbon atom in the position relative to the C(O) group and containing the structural element -(O)C-C-CH- by means of hydrogen in the presence of a base and a ruthenium complex containing a bidentate ligand having coordinating P and N atoms, a monophosphine ligand and anionic and/or uncharged ligands as homogeneous catalyst, with the charge being balanced by one or two monovalent acid anions or a divalent acid anion when uncharged ligands are present.</p> |
申请公布号 |
EP1993984(A1) |
申请公布日期 |
2008.11.26 |
申请号 |
EP20070712475 |
申请日期 |
2007.03.08 |
申请人 |
SOLVIAS AG |
发明人 |
SPINDLER, FELIX;NETTEKOVEN, ULRIKE;PERSEGHINI, MAURO |
分类号 |
C07C29/141;B01J31/24;C07B53/00;C07C29/145;C07C31/135;C07F17/02 |
主分类号 |
C07C29/141 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|