| 摘要 |
Ivabradine (3-(3-(((7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-ylmethyl)methylamino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-bennzazepin-2-one) is used to prepare a medicament for treating endothelial dysfunction. ACTIVITY : Cardiant; Antilipemic; Antidiabetic; Hypotensive; Antiarteriosclerotic; Neuroprotective; Cerebroprotective; Nootropic. Rats with cardiac insufficiency were treated with (I) at a daily dose of 10 mg/kg for 3 months. This prevented endothelial dysfunction in the coronary, renal and cerebral arteries, the dilation of these arteries being similar to that of healthy animals. MECHANISM OF ACTION : None given. |
