| 摘要 |
The invention relates to preparation of multidentate phosphine compounds (1), <CHEM> having a bridging group with substituents A and B from the group of hydrogen, alkyl (C1 to C12), alkoxy, ester, amide or (hetero)aryl (C4 to C14) groups, and 9-phosphabicyclononane groups, wherein a 9-phosphabicyclononane is reacted, in the presence of an acidic catalyst, with a 9-phospha-bicyclononane alkenylmonophosphine (2) <CHEM> with R1, R2 and R3 representing hydrogen, alkyl (C1 to C12), alkoxy, ester, amide or (hetero)aryl (C4 to C14) groups. The invention further relates to novel 9-phospha-bicyclononane alkenylmonophosphines (2), especially P-�2-(2-butenyl)�-9-phospha-bicyclononane, and preparation thereof by transition metal catalysed cross-coupling reaction of 9-phosphabicyclononanes with halogen or sulphonate substituted alkenes. The invention finally more generally relates to preparation of multidentate phosphines (3), <CHEM> having a bridging group substituted by hydrogen and substituents A and B which may be linked together so as to form a ring with the bridging carbon atoms and which can be hydrogen, alkyl (C1 to C12), alkoxy, ester, amide or (hetero)aryl (C4 to C14) groups, wherein an Rc, Rd disubstituted phosphine is reacted, in the presence of an acidic catalyst, with an alkenylmonophosphine compound (4) comprising an Ra, Rb disubstituted phosphine group, Ra to Rd representing alkyl or optionally substituted phenyl groups, of which Ra and Rb, and/or Rc and Rd may be linked together, and which Ra to Rd groups optionally may be substituted by lower alkyl (C1 to C6), or alkoxy groups <CHEM> |
