发明名称 TETRAHYDROISOQUINOLINE SULFONAMIDE DERIVATIVES, THE PREPARATION THEREOF, AND THE USE OF THE SAME IN THERAPEUTICS
摘要 The invention relates to a compound of formula (I) wherein n can represent a value between 1 and 6, -(C)- represents a Сalkylidene group, optionally substituted by between 1 and 4 substituents: Rl represents a hydrogen atom, or a Сalkyl group. R2 represents a hydrogen atom, аСalkyl or Сcycloalkyl group optionally substituted by between 1 and 4 substituents: and В represents NR3R4. R3 and R4 independently representing a Сalkyl group or a hydrogen atom, or together representing a Сalkylidene group, a Сalkenylidene group, аСalkylidene-O-С; alkylidene group, or a Сalkylidene-N(R5)-Сalkylidene group wherein R5 represents a hydrogen atom, or a Сalkyl or Сalkyleaibonyl group, said Сalkyl and Сalkylcarbonyl groups being substitutable; or an aminocycle which is linked by a carbon to the group -NRl-(C)n-, such as aziridine, azetidine, pyrrolidine, piperidine or morpholine; the groups R3, R4, the aminocycle and the nitrogen atom being optionally substituted. The invention can be applied to therapeutics.
申请公布号 UA84771(C2) 申请公布日期 2008.11.25
申请号 UA20060013640 申请日期 2005.05.24
申请人 SANOFI AVENTIS 发明人 DIAZ MARTIN JUAN ANTONIO;JIMENEZ BARGUENO MARIA DOLORES
分类号 C07D217/02;A61K31/47;A61K31/472;A61K31/4725;A61K31/496;A61K31/5377;A61P3/04;A61P3/10;A61P25/00;C07D217/04;C07D217/06;C07D401/12;C07D405/06;C07D409/06 主分类号 C07D217/02
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