发明名称 |
Recombinant Adenovirus Expressing A Gene Encoding Streptolysin O Proetin and Anti-Cancer Composition Comprising Same |
摘要 |
A recombinant adenovirus expressing a streptolysin O (SLO) protein comprising a SLO gene; a promoter operably linked to the SLO gene; a polyadenylation signal sequence; and an adenovirus genome lacking E1 gene effectively kills a cancer cell by expressing a pore-forming toxin, SLO protein, and, therefore, is useful for the suicide cancer gene therapy.
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申请公布号 |
US2008286238(A1) |
申请公布日期 |
2008.11.20 |
申请号 |
US20060091504 |
申请日期 |
2006.10.26 |
申请人 |
KIM CHUL WOO;YANG WAN SEOK;KIM MIN KYOUNG |
发明人 |
KIM CHUL WOO;YANG WAN SEOK;KIM MIN KYOUNG |
分类号 |
A61K35/76;A61P31/00;C12N7/00 |
主分类号 |
A61K35/76 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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