SECRETED STAPHYLOCOCCUS AUREUS PROTEINS AND PEPTIDES FOR USE IN INHIBITING ACTIVATION OF THE COMPLEMENT SYSTEM
摘要
Compounds comprising peptides and peptide analogs capable of binding the C3 protein and inhibiting complement activation are disclosed. These compounds mimic the structure and activity of secreted Staphylococcus aureus proteins, Efb and the previously uncharacterized SAVl 155.
申请公布号
WO2008140637(A2)
申请公布日期
2008.11.20
申请号
WO2008US01662
申请日期
2008.02.06
申请人
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;LAMBRIS, JOHN, D.;GEISBRECHT, BRIAN, B.