发明名称 |
Antisense Oligonucleotides Against Cpla2, Compositions and Uses Thereof |
摘要 |
Antisense oligonucleotides against cPLA<SUB>2 </SUB>are provided, which are capable of inhibiting cPLA<SUB>2 </SUB>expression as well as superoxide production, especially in phagocytes. These antisense oligonucleotides are powerful agents for the treatment of inflammatory conditions, in particular arthritis, as well as in neurodegenerative diseases. The antisense oligonucleotides or compositions comprising the same may be used in methods of treatment of such diseases.
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申请公布号 |
US2008287380(A1) |
申请公布日期 |
2008.11.20 |
申请号 |
US20050568169 |
申请日期 |
2005.04.17 |
申请人 |
MOR RESEARCH APPLICATIONS LTD.;BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY |
发明人 |
LEVY RACHEL |
分类号 |
A61K31/711;C07H21/04;C12N;C12N5/02;C12N15/113 |
主分类号 |
A61K31/711 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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