摘要 |
A medical device, for example a stent, has a surface which in use contacts body tissue, wherein said surface has on it a biocompatible coating layer comprising a polymer having covalently bound allyl-terminated pendent groups, said pendent groups comprising a moiety selected from -0-CH<SUB>2</SUB>-CH=CH<SUB>2</SUB> -S-CH<SUB>2</SUB>-CH=CH<SUB>2</SUB> -S (=0) -CH<SUB>2</SUB>-CH=CH<SUB>2</SUB> -Se-CH<SUB>2</SUB>-CH=CH<SUB>2</SUB> and -Se (=0 J-CH<SUB>2</SUB>-CH=CH<SUB>2</SUB>. This surface has good biocompatibility and can bind strongly to a metallic surface. The polymer may be made from an electropolymerisable monomer, e.g. a pyrrole. |
申请人 |
CHAMELEON BIOSURFACES LIMITED;PICKETT, CHRISTOPHER JOHN;BOOTE, TIMOTHY JAMES;IBRAHIM, SAAD KHALIL;KNOTT, JANE MARIE;TOLLAND, JOHN DOUGLAS |
发明人 |
PICKETT, CHRISTOPHER JOHN;BOOTE, TIMOTHY JAMES;IBRAHIM, SAAD KHALIL;KNOTT, JANE MARIE;TOLLAND, JOHN DOUGLAS |