TARGETING OF FRUCTOKINASE AS THERAPY FOR CARDIOVASCULAR DISEASE, METABOLIC SYNDROME, AND RENAL DISEASE
摘要
Disclosed herein are methods of treating and/or preventing hypertension, metabolic syndrome, and/or renal disease that involve the targeting of Fructokinase (ketohexokinase). Also disclosed herein are methods of screening for inhibitors of Fructokinase. Further disclosed herein are methods of formulating a prescriptive regimen for hypertension, metabolic syndrome, and/or renal disease that comprises evaluating the level of ketohexokinase activity in an individual.
申请公布号
WO2008024902(A3)
申请公布日期
2008.11.20
申请号
WO2007US76624
申请日期
2007.08.23
申请人
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.;JOHNSON, RICHARD, J.;NAKAGAWA, TAKAHIKO;SEGAL, MARK, S.;SAUTIN, YURI, Y.
发明人
JOHNSON, RICHARD, J.;NAKAGAWA, TAKAHIKO;SEGAL, MARK, S.;SAUTIN, YURI, Y.