发明名称 |
Optically active isomers of ketotifen and therapeutically active metabolites thereof |
摘要 |
Racemic norketotifen, racemic 10-hydroxy-ketotifen, racemic 10-hydroxy-nor-ketotifen and optically active isomers of ketotifen, norketotifen, 10-hydroxy-ketotifen and 10-hydroxy-norketotifen were found to have antiallergic and anti-inflammatory effects while being devoid of the severe dose-limiting sedative side effects of Ketotifen.
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申请公布号 |
US2008287498(A1) |
申请公布日期 |
2008.11.20 |
申请号 |
US20070796998 |
申请日期 |
2007.04.30 |
申请人 |
ABERG A K GUNNAR;WRIGHT GEORGE E;CHEN JAN L;MAIOLI ANDREW T |
发明人 |
ABERG A.K. GUNNAR;WRIGHT GEORGE E.;CHEN JAN L.;MAIOLI ANDREW T. |
分类号 |
A61K31/4535;A61K9/08;A61K9/10;A61K9/12;A61K45/00;A61P1/00;A61P1/04;A61P1/14;A61P9/00;A61P11/00;A61P11/06;A61P11/08;A61P17/00;A61P17/04;A61P19/00;A61P27/02;A61P27/16;A61P29/00;A61P37/08;C07D409/04;C07D409/08 |
主分类号 |
A61K31/4535 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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