POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF
摘要
Disclosed are compounds having polybasic functionalities. The compounds inhibit bacterial efflux pump inhibitors and are used in combination with an anti-bacterial agent to treat or prevent bacterial infections. These combinations can be effective against bacterial infections that have developed resistance to anti-bacterial agents through an efflux pump mechanism.
申请公布号
WO2008141010(A2)
申请公布日期
2008.11.20
申请号
WO2008US62785
申请日期
2008.05.06
申请人
MPEX PHARMACEUTICALS, INC.;GLINKA, TOMASZ;LOMOVSKAYA, OLGA;BOSTIAN, KEITH;WALLACE, DAVID, M.
发明人
GLINKA, TOMASZ;LOMOVSKAYA, OLGA;BOSTIAN, KEITH;WALLACE, DAVID, M.