PRODUCTION OF A HOMOGENEOUS CELL LINE HIGHLY PERMISSIVE TO PORCINE CIRCOVIRUS TYPE 2 (PCV2) INFECTION

摘要

Continuous cell lines that are highly permissive to infection by porcine circovirus type 2 ("PCV2") are described. PCV2 is the causal agent of post-w eaning multi-systemic wasting syndrome ("PMWS") in pigs. PMWS has emerged as a major disease that poses a significant threat to the economics of global swine industry. The highly permissive cell lines of this invention provide e fficient and reliable sources of PCV2 for use in development of vaccines, th erapies and diagnostic agents for PMWS.