| 摘要 |
A medical device, for example a stent, has a surface which in use contacts body tissue, and the surface has on it a biocompatible coating layer comprising a polymer, such as polypyrroles, polythiophenes, polyanilines, polyamides, polyaminoacids, polysaccharides, polyesters, polyalkenes, polyamines, polyethers, polyethyleneterephthalates, polyimides, polysiloxanes, polyphosphazines, polylactides, polyglycolides, polycaprolactones, polydioxanones, polygluconates, polyanhydrides, polyphosphoesters, polyorthoesters or polyphosphate esters. The polymer has covalently bound allyl-terminated pendent groups, the pendent groups comprising a moiety are selected from -O-CH2-CH=CH2, -S-CH2-CH=CH2 -S(=O)-CH2-CH=CH2, -Se-CH2-CH=CH2 and -Se(=O)-CH2-CH=CH2. Also disclosed, is a method of manufacture of the medical device comprising electro polymerisation of one or more monomers comprising the foregoing pendent groups. |
