PEPTIDE VACCINE FOR INDUCING PRODUCTION OF ANTI-AMYLOID- -PEPTIDE ANTIBODY

摘要

An object of the present invention is to provide a peptide vaccine for preventing and/or treating diseases caused by amyloid ²-peptide, such as Alzheimer's disease. The present invention solves the above object by providing a peptide vaccine constructed by inserting a peptide having an amino acid sequence of a cell attachment motif of a cell adhesive molecule to a peptide which consists of a peptide having an amino acid sequence of multiagretope type T-cell epitope, which has been generated immunological memory, or a peptide including the same; an linker peptide; and a peptide having an amino acid sequence of a B cell epitope which is a specific region of amyloid ²-peptide or a peptide including the same.