发明名称 |
PSEUDOINFECTIOUS FLAVIVIRUS AND USES THEREOF |
摘要 |
The present invention discloses a replication-deficient pseudoinfective virus belonging to the Flaviviridae family that lack the capsid gene, where the replication-deficient pseudoinfective virus propagates only in cells expressing the capsid or capsid, prM and envelope protein of the flavivirus. The present also discloses the method of producing such viruses on a large scale and the use of these pseudoinfective viruses as vaccines for preventing diseases caused by infections of humans or animals by the viruses belonging to this family. |
申请公布号 |
EP1991709(A2) |
申请公布日期 |
2008.11.19 |
申请号 |
EP20070751696 |
申请日期 |
2007.02.27 |
申请人 |
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
FROLOV, ILYA;FROLOVA, ELENA;MASON, PETER C. |
分类号 |
A61K39/12;C12N5/00;C12N7/00 |
主分类号 |
A61K39/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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