Substituted piperidines as therapeutic compounds

摘要

Use of compounds of the general formula (1)
<Chemistry id="chema01" num="0001"><Image id="ia01" he="54" wi="49" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry>
and pharmaceutically acceptable salt thereof, in which R<Sup>1</Sup>, R<Sup>2</Sup>, R<Sup>3</Sup>, R<Sup>4</Sup>, W, X, Z and n have the definitions illustrated in detail in the description, as beta-secretase, cathepsin D, plasmepsin II and/or HIV protease inhibitors.