发明名称 |
Collagen fibrils carrying bioactive heterologous domains and their use in e.g. wound healing |
摘要 |
<p>A modified pro-± chain comprising a triple helix forming domain linked to at least an N-terminal domain, the N-terminal domain containing a polypeptide from at least part of a laminin glycoprotein or secretory leukocyte protease inhibitor. The pro-± chain may form part of a procollagen molecule that has the N-terminal domain retained. The procollagen molecules may be incorporated into collagen polymers, matrices and gels and be used for such applications as wound healing.</p> |
申请公布号 |
EP1992642(A1) |
申请公布日期 |
2008.11.19 |
申请号 |
EP20080010644 |
申请日期 |
2004.04.21 |
申请人 |
THE UNIVERSITY OF MANCHESTER |
发明人 |
ASHCROFT, GILLIAN;BULLEID, NEIL;KADLER, KARL |
分类号 |
A61K38/00;C07K14/78;A61K38/39;A61L15/32;A61L27/22;A61L27/24;A61L27/60;A61P17/02;C07K14/81;C12N15/62 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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