METHODEN ZUR BEHANDLUNG VON TUMOREN UND METASTASEN UNTER VERWENDUNG EINER ANTI-ANGIOGENEN UND IMMUN-THERAPIEN

摘要

The invention provides methods for treating tumors and tumor metastases in a mammal comprising administering, to a mammal in need of treatment, a therapeutic amount of an antagonist sufficient to inhibit angiogenesis in combination with a therapeutic amount of anti-tumor immunotherapeutic agent, such as a anti-tumor antigen antibody/cytokine fusion protein having a cytokine and a recombinant immunoglobulin polypeptide chain sufficient to elicit a cytokine-specific biological response.