摘要 |
The embodiments provide macrocyclic compounds of the general Formula I, a s well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, includi ng methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individ ual in need thereof an effective amount of a subject compound or composition .
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申请人 |
INTERMUNE, INC.;ARRAY BIOPHARMA INC. |
发明人 |
KERCHER, TIMOTHY;LYON, MICHAEL;WANG, BIN;SCHUMACHER, ANDREAS;BEIGELMAN, LEONID;SEIWERT, SCOTT;ANDREWS, STEVEN W.;MARTIN, PIERRE;KAUS, ROBERT;LIU, JYANWEI;CONDROSKI, KEVIN;JIANG, YUTONG;KENNEDY, APRIL;PAN, LIN;BLATT, LAWRENCE M. |