PREVENTION OF CANCERS BY IMMUNIZATION

摘要

In healthy subjects, especially the ones with increased risk for developing cancer due to genetic predisposition or other risk factors, cancer can be prevented by immunization with a cancer vaccine. Oncoantigens present in the vaccine preferably are incubated with IFN-?, IL-2 or both. To prevent cancer recurrence, cancer patients in remission are given a prolonged course of immunizations with a vaccine that includes, for example, oncoantigens in combination with immune competent cells (e.g, bone marrow and T lymphocytes). The bone marrow and T lymphocytes are optionally treated with IFN-?, IL-2 or both.