发明名称 Verfahren zur Herstellung neuer Guanidin-Verbindungen
摘要 <p>Novel cpds. of formula: (where X = H, halogen, HOCH2 or Me, R1 = H, lower alkyl, benzyl or phenethyl (opt. rng-substd by 1 or 2 of halogen, lower alkyl or alkoxy), or 3-6C cycloalkyl, R2 = H, OH or lower alkyl, or (when R1 = H), Me2N or allyl, or NR1R2 is morpholino, 1-pyrrolidinyl, piperidino, 1-azepinyl, 4-methyl-, 4-(2-hydroxyethyl)- or 4-phenyl-1-piperazinyl (opt. mono-substd. in the phenyl ring by halogen Me or NO2)) are prepd. by reacting the corresp. S-lower alkyl-isothiourea deriv. with NHR1R2, preF. in the presence of acid. The products are circulatory-active agents, saliuretics, antiphlogistics and psychotherapeutic agents.</p>
申请公布号 CH517730(A) 申请公布日期 1972.01.15
申请号 CH19690015859 申请日期 1969.10.24
申请人 SANDOZ AG 发明人 BORMANN,GERHARD;GMUENDER,JOHN,DR.;TROXLER,FRANZ,DR.;WILKENS,HEINRICH,DR.
分类号 C07D209/90;(IPC1-7):C07D27/04 主分类号 C07D209/90
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