| 发明名称 |
Spiro-piperidine derivatives |
| 摘要 |
The present invention is concerned with novel spiro-piperidine derivatives as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are useful in the prevention and/or treatment of anxiety and depressive disorders and other diseases. In particular, the present invention is concerned with compounds of the general formula (I) wherein R<SUP>1 </SUP>to R<SUP>5</SUP>, R<SUP>5</SUP>', X, Y and A are as defined in the specification.
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| 申请公布号 |
US2008280898(A1) |
申请公布日期 |
2008.11.13 |
| 申请号 |
US20070955434 |
申请日期 |
2007.12.13 |
| 申请人 |
BISSANTZ CATERINA;GRUNDSCHOBER CHRISTOPHE;MASCIADRI RAFFAELLO;RATNI HASANE;ROGERS-EVANS MARK;SCHNIDER PATRICK |
发明人 |
BISSANTZ CATERINA;GRUNDSCHOBER CHRISTOPHE;MASCIADRI RAFFAELLO;RATNI HASANE;ROGERS-EVANS MARK;SCHNIDER PATRICK |
| 分类号 |
A61K31/438;A61K31/5377;A61P9/00;A61P25/00;C07D265/30;C07D401/04 |
主分类号 |
A61K31/438 |
| 代理机构 |
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