发明名称 |
POLYMER-SURFACTANT NANOPARTICLES FOR SUSTAINED RELEASE OF COMPOUNDS |
摘要 |
A polymer-surfactant nanoparticle formulation, using the anionic surfactant aerosol OT (AOT) and polysaccharide polymer alginate, is used for sustained release of water-soluble drugs. The AOT-alginate nanoparticles are suitable for encapsulating doxorubicin, verapamil and clonidine, as well as therapeutic agents effective against dermal conditions such as psoriasis. The nanoparticles are also suitable for encapsulating photo-activated compounds such as methylene blue for use in photo-dynamic therapy of cancer and other diseases, and for treating tumor cells that exhibit resistance to at least one chemotherapeutic drug. |
申请公布号 |
WO2008022146(A3) |
申请公布日期 |
2008.11.13 |
申请号 |
WO2007US75925 |
申请日期 |
2007.08.14 |
申请人 |
WAYNE STATE UNIVERSITY;PANYAM, JAYANTH;PATIL, MAHESH, D. CHAVAN |
发明人 |
PANYAM, JAYANTH;PATIL, MAHESH, D. CHAVAN |
分类号 |
A61K39/395 |
主分类号 |
A61K39/395 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|