METHOD FOR THE PRODUCTION OF BIO-ACTIVE SUBSTANCES FROM THE NOVEL ACTINOMYCETE TAXA MAR3A AND MAR3B BELONGING TO THE FAMILY STREPTOMYCETACEAE

摘要

This invention provides a method for the isolation and identification of marine actinomycetes tentatively named MAR3A and MAR3B and the use of these groups as a source of new biologically active compositions including pharmaceuticals. The method includes specifics about where these microorganisms occur and their culture requirements. It also provides information describing characteristic DNA sequences that are used to identify members of this group and information demonstrating that members produce metabolites with significant activities in pharmaceutically relevant bioassays.