| 摘要 |
Isolated apoptotic epithelial scaffolds are disclosed The scaffolds find use in promoting re-vascularization of wounded tissues Provided are isolated or ex vivo trl-layered cell sorted tissues which are comprised of a bottom layer comprised of an apoptotic epithelial scaffold a middle layer comprised of mesenchymal cells, and a top layer comprised of non-differentiated epithelial cells In vitro methods are disclosed for generating isolated or ex vivo tri-layered cell sorted tissues by exposing cultured mixtures of epithelial and mesenchymal cells to an inflammatory cytokine Further provided are methods of promoting wound healing and re-vasculapzation of wounds by contacting wounded tissue with the apoptotic epithelial scaffolds |
