摘要 |
<P>PROBLEM TO BE SOLVED: To provide a device for delivering insulin to a subject with impaired hepatic glucose processing. <P>SOLUTION: The device delivers a series of pulses of insulin to the subject accompanied by ingestion of glucose in the form of a carbohydrate containing meal. The amount of insulin in each pulse, the interval between pulses and the amount of time to deliver each pulse to the subject are selected so that initially after ingestion of the carbohydrate containing meal, the subject's circulating blood glucose level rises, and then an amount as much as not lower than 50 mg/dL falls. <P>COPYRIGHT: (C)2009,JPO&INPIT |