| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide peptides exhibiting immunochemical reaction to antibodies against Epstein-Barr virus (EBV) which is human herpes virus, and monoclonal antibodies and anti-idiotypic antibodies against these peptides. <P>SOLUTION: The invention relates to a peptide or fragment thereof which is immunochemically reactive with Epstein-Barr Virus (EBV) antibodies. A new monoclonal antibody directed to the peptide or fragment thereof is also part of the invention. The invention also relates to a method for the detection of EBV or anti-EBV antibodies in a test fluid and also to an immunochemical reagent comprising a peptide, a fragment or a polypeptide according to the invention and a test kit to be used when applying the detection methods. Detection of EBV in a test fluid or tissue specimen using antibodies, monoclonal and polyclonal, directed to the peptide, which have the characteristics of detecting both native and denatured intact, functional EBNA-1 protein is also part of the present invention. <P>COPYRIGHT: (C)2009,JPO&INPIT</p> |
