| 发明名称 |
USE OF A GLIAL ATTENUATOR TO PREVENT AMPLIFIED PAIN RESPONSES CAUSED BY GLIAL PRIMING |
| 摘要 |
<p>The use of a glial attenuator, such as ibudilast (3-isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine), to prevent the negative consequences of glial priming is described. In particular, the present invention is directed to a method of treating a subject with ibudilast to prevent amplified pain responses to inflammation or injury as a result of glial priming following an initial glial activating event.</p> |
| 申请公布号 |
WO2008137012(A1) |
申请公布日期 |
2008.11.13 |
| 申请号 |
WO2008US05582 |
申请日期 |
2008.05.01 |
| 申请人 |
AVIGEN, INC.;THE REAGENTS OF THE UNIVERSITY OF COLORADO;JOHNSON, KIRK W.;WATKINS, LINDA R. |
发明人 |
JOHNSON, KIRK W.;WATKINS, LINDA R. |
| 分类号 |
A61K31/437;A61P25/00 |
主分类号 |
A61K31/437 |
| 代理机构 |
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| 主权项 |
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