METHODS AND COMPOSITIONS USING MUTANT GP120

摘要

Compositions and methods for eliciting an immune response against HIV and/or SIV are provided. Isolated gpl20 proteins having two or more amino acids deleted from their ß3-ß5 loop regions and isolated nucleic acid sequences encoding a gpl20 protein having two or more amino acids deleted from its ß3-ß5 loop region are also provided.