The invention provides inhibitors of Wnt signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I: wherein R1 to R7 and Z are as defined herein.
申请公布号
WO2008137408(A1)
申请公布日期
2008.11.13
申请号
WO2008US61864
申请日期
2008.04.29
申请人
GENENTECH, INC.;CURIS, INC.;BRUNTON, SHIRLEY ANN;GUNZNER, JANET L.;COULTER, TOM;STIBBARD, JOHN H. A.;MARSTERS, JR., JAMES C.
发明人
BRUNTON, SHIRLEY ANN;GUNZNER, JANET L.;COULTER, TOM;STIBBARD, JOHN H. A.;MARSTERS, JR., JAMES C.
