| 摘要 |
PROBLEM TO BE SOLVED: To provide a method for producing hIGF-I with high purity and yield. SOLUTION: The method for producing human insulin-like growth factor I is provided, which method comprises a step of removing modified human insulin-like growth factor I, wherein the step comprises (A) a step of adjusting the pH of a culture liquid of a human insulin-like growth factor I producing bacteria to 8 or higher after completion of culture, (B) a step of letting the culture liquid obtained in the step (A) stand, and (C) a step of removing the producing bacteria from the culture liquid obtained in the step (B). COPYRIGHT: (C)2009,JPO&INPIT
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