发明名称 |
Inhibitors of Akt Activity |
摘要 |
The present invention is directed to compounds which contain substituted pyridazines and pyrimidines moieties which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration (if the compounds of the invention.
|
申请公布号 |
US2008280889(A1) |
申请公布日期 |
2008.11.13 |
申请号 |
US20050547367 |
申请日期 |
2005.04.05 |
申请人 |
BILODEAU MARK T;CHUA PETER C;COSFORD NICHOLAS D P;HOFFMAN JACOB M;NAGASAWA JOHNNY YASUO |
发明人 |
BILODEAU MARK T.;CHUA PETER C.;COSFORD NICHOLAS D.P.;HOFFMAN JACOB M.;NAGASAWA JOHNNY YASUO |
分类号 |
A61K31/501;A61K31/506;A61K31/5377;A61K31/541;A61P35/00;C07D401/14;C07D403/00;C07D403/10;C07D403/14;C07D413/14;C07D417/14 |
主分类号 |
A61K31/501 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|