发明名称 |
PYRIMIDINE DERIVATIVES AND COMPOSITIONS AS C-KIT AND PDGFR KINASE INHIBITORS |
摘要 |
<p>The invention provides a novel class of pyrimidine derivatives, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of c-kit, PDGFRa and PDGFRß kinases.</p> |
申请公布号 |
WO2008137605(A1) |
申请公布日期 |
2008.11.13 |
申请号 |
WO2008US62304 |
申请日期 |
2008.05.01 |
申请人 |
IRM LLC;LI, XIAOLIN;LU, XIAODONG;MOLTENI, VALENTINA |
发明人 |
LI, XIAOLIN;LU, XIAODONG;MOLTENI, VALENTINA |
分类号 |
C07D401/14;A61K31/444;A61P35/00;C07D405/14 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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