发明名称 |
Humanized Anti-Tag-72 Monoclonal Antibodies |
摘要 |
The present invention relates to humanized antibodies specific to a tumor associated glycoprotein, TAG-72, and anticancer compositions comprising the humanized antibodies. In detail, the present invention relates to a humanized antibody which has enhanced antigen binding affinity by mutating a heavy chain of a humanized antibody PXA/HzK specific for TAG-72, an antibody which is prepared by replacing a light chain of the humanized antibody with a human light chain, and anticancer compositions including the antibodies.
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申请公布号 |
US2008279847(A1) |
申请公布日期 |
2008.11.13 |
申请号 |
US20050628423 |
申请日期 |
2005.05.06 |
申请人 |
HONG HYO JEONG;KIM SANG JICK;YOON SUN OK;JANG MYEONG HEE;KIM KEUN SOO;LEE TAE SUP;CHOI CHANG WOON |
发明人 |
HONG HYO JEONG;KIM SANG JICK;YOON SUN OK;JANG MYEONG HEE;KIM KEUN SOO;LEE TAE SUP;CHOI CHANG WOON |
分类号 |
A61K39/395;A61P31/00;A61P35/04;C07K16/18;C07K16/30;C12N5/06;C12N15/00;C12N15/11;C12P21/04;G01N33/574 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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