METHODS AND COMPOSITIONS FOR UPREGULATION OF GATA ACTIVITY
摘要
<p>A novel method of identifying compounds capable of upregulating GATA activity is disclosed. The method includes providing a sample of cells that express GATA, providing a sample of a candidate compound, contacting the cell sample and the compound sample, and measuring a quantitative indicator of GATA activity within the cell sample after the contacting step. GATA inducers identified by the method and uses therefore to upregulate GATA activity in subjects and to prevent or treat atherosclerosis or diabetes in subjects are also described.</p>
申请公布号
WO2008137533(A1)
申请公布日期
2008.11.13
申请号
WO2008US62198
申请日期
2008.05.01
申请人
REDDY US THERAPEUTICS, INC.;POLIKANDRIOTIS, JOHN, ANASTASIOS;PILLARISETTI, SIVIRAM;KHANNA, ISH;SAXENA, UDAY