摘要 |
1307516 Enzyme-containing foods M HOOREMAN 20 Feb 1970 [21 Feb 1969] 9619/69 Heading A2B [Also in Divisions A5 and C3] A proteolytic enzyme-containing composition is capable of reducing the viscosity in viro of intestinal, bronchial or cervical mucus, and is insensitive to naturally occurring trypsin inhibitors. The activity of the composition is such that, under standard test conditions, the viscosity reduction is within the range (5 % more than trypsin) to (5% less than chymotrypsin), e.g. 65-35%, compared with untreated mucus. The composition may be prepared by fermentation of Streptomyces fradiae (Strains 1998 or 2019 of the National Natural History Museum, Paris) e.g. for 60-84 hours at 28‹C in a medium containing 30 gm/l soya flour, 30 gm/l. glucose, 0.8 gm/l disodium phosphate and 10 gm/l CaCO 3 and buffered to pH 7.0, while aerating with 0.3 L/L sterile air per minute. |