发明名称 |
ENGINEERED ANTIBODY-STRESS PROTEIN FUSIONS |
摘要 |
<p>Provided are fusion polypeptides comprising an engineered antibody and a stress protein that bind to antigens with high affinity, are highly immunogenic, exhibit MHC class I priming and are able to be produced in non-mammalian cells, such as E. coli.</p> |
申请公布号 |
EP1988927(A2) |
申请公布日期 |
2008.11.12 |
申请号 |
EP20070811793 |
申请日期 |
2007.02.02 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
GELFAND, JEFFREY A. |
分类号 |
A61K49/00;A61K38/00;A61K39/00;A61K39/02;A61K39/04;A61K39/385;A61K39/395;A61K39/40;A61K45/00;C07H21/02;C07H21/04 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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